MailTalkX is a spam blocker and an email monitoring tool.
It is an email monitoring and a Spam filtering utility. It supports multiple mailboxes. It allows you to check each mailbox automatically at inidividually specified intervals and can notify you of new mail with pop-up messages, sound clips and/or AVI. And With MailTalkX filtering you can control spam, personalize the audio notification of new mail, automatically forward or reply to messages and even trigger other applications or utilities. MailTalkX is 100% network compatible.
http://www.softbytelabs.com/us/mx/index.html